MyBioSource.com's HBEGF Rabbit mAb is a Rabbit monoclonal antibody. The HBEGF Rabbit mAb Antibody was generated using HBEGF as the antigen. It reacts with Human, and Rat. This antibody has been shown to work in applications such as: Western Blot.
Description
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.SitesFeature keyPosition(s)Description